European Journal of Clinical and Biomedical Sciences

Volume 3, Issue 4, August 2017

  • Non-Steroidal Anti-Inflammatory Drugs and Vitamin C in the Rotenone Induced Nigrostriatal Damage in Mice

    Nagi Ali Ibrahim, Omar Mohamed Abdel-Salam, Yasser Ashry Khadrawy, Amal Mohamed Hashem, Eman Mohamed Sameer

    Issue: Volume 3, Issue 4, August 2017
    Pages: 67-79
    Received: Apr. 15, 2017
    Accepted: May 20, 2017
    Published: Jul. 04, 2017
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    Abstract: The nigrostriatal pathway is a dopaminergic pathway that connects the substantia nigra with the dorsal striatum. Loss of dopamine neurons in the substantia nigra is one of the main pathological features of Parkinson's disease, leading to a marked reduction in dopamine function in this pathway. This study aimed at evaluating the protective role of t... Show More
  • Band 3 Protein Function and Oxidative Stress in Erythrocytes from Systemic Sclerosis Patients with Interstitial Lung Disease

    Rossana Morabito, Alessia Remigante, Gianluca Bagnato, William Neal Roberts, Davide Sciortino, Tommaso D’Angelo, Filippo Iannelli, Dario Iannelli, Francesca Cordova, Mariateresa Cirillo, Giuseppina La Spada, Angela Marino

    Issue: Volume 3, Issue 4, August 2017
    Pages: 80-84
    Received: May 16, 2017
    Accepted: Jun. 28, 2017
    Published: Jul. 27, 2017
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    Abstract: A link between reactive oxygen species (ROS) and Systemic Sclerosis (SSc) development has been already described, along with an oxidative stress-induced reduction of anion exchange capability through Band 3 protein. On this basis, blood from SSc patients has been collected to measure the rate constant for SO4= uptake, which is an index for anion ex... Show More